According to the characteristics and actual situation of Yellow River pumping station project in Jining, a foundation treatment scheme combining precast pipe pile (PHC) and cement mixing pile is proposed in this paper. The precast pipe pile (PHC) is mainly to improve the bearing capacity of the foundation and reduce the settlement of the foundation, so as to solve the problem of insufficient bearing capacity and excessive settlement. Cement mixing pile enclosing wall is used to improve the anti-vibration liquefaction ability of foundation. The technology of this project can provide scheme reference and idea reference for similar water project design.